Comparative evaluation of the effectiveness of a peptide-containing drug and polyoxydonium in the treatment of chronic parodontitis

Currently, the available methods of treating parodontitis are not able to have a complex effect. Therefore, in recent years, there has been an active search and development new treatment drugs that etiopathogenetic effect on this disease. This article provides comparative evaluation classical experimental chronic periodontitis. Based reconstruction model inflammation periodontal tissues Wistar rat line, we compared topical therapy by “Organosilicon Glycerohydrogel – Peptide” “Polyoxidonium” compositions. A assessment activity these with control groups, which were treated Glycerohydrogel” “Metrogyl Denta”, was carried out. Previously, out separate studies effectiveness use composition “organosilicon glycerohydrogel peptide”, as well method periodontitis, injecting drug “Polyoxidonium”. They classic for disease obtain relevant data results. In our opinion, obtained considerable interest. The comparison clinical histological out, showed all had positive processes tissue regeneration. However, Glycerohydrogel-peptide”, due characteristics hydrogel, is acting transcutaneous conductor, faster antimicrobial pathogenetic effect, allows comprehensive approach solving problem. groups “Polyoxidonium”, period improvement increased 57% group “Glycerohydrogel-Peptide”, and, Denta” group, indicators improved 15% approximately.